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You are here:Home » Antibodies » Abs to Enzymes, Racemase » Anti -AMACR, CT (RM, RACE, CBAS4, AMACRD)

Anti -AMACR, CT (RM, RACE, CBAS4, AMACRD)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IC
This gene encodes a racemase. The encoded enzyme interconverts pristanoyl-CoA and C27-bile acylCoAs between their (R)-and (S)-stereoisomers. The conversion to the (S)-stereoisomers is necessary for degradation of these substrates by peroxisomal beta-oxidation. Encoded proteins from this locus localize to both mitochondria and peroxisomes. Mutations in this gene may be associated with adult-onset sensorimotor neuropathy, pigmentary retinopathy, and adrenomyeloneuropathy due to defects in bile acid synthesis. Alternatively spliced transcript variants have been described.
Catalog #143134
ApplicationsSuitable for use in Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No13k7
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM NaCl, 0.2% sodium azide, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenPurified recombinant human AMACR (C-terminal) protein fragments expressed in E. coli.
SpecificityRecognizes endogenous levels AMACR(C-terminus). Does not cross-react with related proteins. Species Crossreactivity: rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names(RM, RACE, CBAS4, AMACRD)


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