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You are here:Home » Antibodies » Abs to Arrestin » Anti -Arrestin 1, beta (ARB 1, ARB 1, ARB1, ARB1, ARR 1, ARR 1, ARR1, ARR1, ARRB 1, ARRB1, ARRB1, ARRB1_HUMAN, Arrestin 2, Arrestin beta 1, Arrestin beta-1, Beta-arrestin-1.)

Anti -Arrestin 1, beta (ARB 1, ARB 1, ARB1, ARB1, ARR 1, ARR 1, ARR1, ARR1, ARRB 1, ARRB1,
ARRB1, ARRB1_HUMAN, Arrestin 2, Arrestin beta 1, Arrestin beta-1, Beta-arrestin-1.)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 1 is a cytosolic protein and acts as a cofactor in the beta-adrenergic receptor kinase (BARK) mediated desensitization of beta-adrenergic receptors. Besides the central nervous system, it is expressed at high levels in peripheral blood leukocytes, and thus the BARK/beta-arrestin system is believed to play a major role in regulating receptor-mediated immune functions. Alternatively spliced transcripts encoding different isoforms of arrestin beta 1 have been described. [provided by RefSeq, Jan 2011]
Catalog #143137
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeLgG2b
Clone No13k10
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM NaCl, 0.2% sodium azide, 0.1mg/ml BSA, 50% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenPurified recombinant human ARRB1 protein fragments expressed in E. coli.
SpecificityRecognizes endogenous levels of ARRB1. Does not cross-react with related proteins. Species Crossreactivity: mouse, rat, human
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate names(ARB 1, ARB 1, ARB1, ARB1, ARR 1, ARR 1, ARR1, ARR1, ARRB 1, ARRB1, ARRB1, ARRB1_HUMAN, Arrestin 2, Arrestin beta 1, Arrestin beta-1, Beta-arrestin-1.)


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