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You are here:Home » Molecular Biology » MB-Growth Factors-Eotaxin » Eotaxin, Recombinant, Human (CCL11)

Eotaxin, Recombinant, Human (CCL11)


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Eotaxin is a CC chemokine that signals through the CCR3 receptor.It is produced by IFN-gamma stimulated endothelial cells and TNF-activated monocytes.Eotaxin selectively chemoattracts eosinophils and along Eotaxin-2 and Eotaxin-3, plays a key role in the regulation of eosinophil recruitment in the asthmatic lung, and in allergic reactions.Recombinant human Eotaxin is an 8.3kD protein containing 74 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Catalog #143316
Biological ActivityDetermined by its ability to chemoattract human peripheral blood eosinophils using a concentration range of 0.1-10.0ng/ml.
CrossreactivityMouse, Human, Hamster, Human, Guinea Pig
Quality ControlVerified by N-terminal and Mass Spectrometry analyses (when applicable).
Endotoxin<0.1ng/ug of protein (<1EU/ug).
Protein ContentVerified by UV Spectroscopy and/or SDS-PAGE gel.
Storage and StabilityStore lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein.
SourceE. coli
Purity98% by SDS-PAGE gel and HPLC analyses.
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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