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You are here:Home » Molecular Biology » Growth Factors-CCL » CCL14, Recombinant, Human, 66aa (C-C Motif Chemokine 14, Chemokine CC-1/CC-3, HCC-1/HCC-3, HCC-1(1-74), NCC-2, Small-inducible Cytokine A14, NCC2, SCYA14)

CCL14, Recombinant, Human, 66aa (C-C Motif Chemokine 14, Chemokine CC-1/CC-3, HCC-1/HCC-3,
HCC-1(1-74), NCC-2, Small-inducible Cytokine A14, NCC2, SCYA14)

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Specifications

HCC-1 is a CC chemokine that signals through the CCR1 receptor and chemoattracts blood monocytes. It is secreted by various tissues including skeletal muscle, heart, spleen, liver, bone marrow and plasma. Mature HCC-1 is found in four different forms, which are distinguished by differential N-terminal truncation and contain 74, 72, 71, or 66aa residues. Recombinant human HCC-1 (66aa) is a 7.8kD protein consisting of 66aa including the four highly conserved residues present in CC chemokines.
Catalog #143354
Biological ActivityDetermined by its ability to chemoattract human monocytes using a concentration range of 5-20ng/ml.
AA SequenceGPYHPSECCF TYTTYKIPRQ RIMDYYETNS QCSKPGIVFI TKRGHSVCTN PSDKWVQDYI KDMKEN
Quality ControlVerified by N-terminal and Mass Spectrometry analyses (when applicable).
Endotoxin<0.1ng/ug of protein (<1EU/ug).
Protein ContentVerified by UV Spectroscopy and/or SDS-PAGE gel.
Storage and StabilityStore lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein.
SourceE. coli
Purity98% by SDS-PAGE gel and HPLC analyses.
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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