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You are here:Home » Growth Factors, Cytokines » Growth Factors-Interleukin » IL-11, Recombinant, Mouse (AGIF (Adipogenesis inhibitory factor))

IL-11, Recombinant, Mouse (AGIF (Adipogenesis inhibitory factor))

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Specifications

IL-11 is a multifunctional cytokine produced by stromal cells such as fibroblasts, epithelial cells and osteoclasts.It is expressed in a wide variety of tissues including thymus, lung, bone, connective tissue and central nervous system.IL-11 plays an important regulatory role in hematopoiesis by stimulating growth of myeloid, erythroid and megakaryocyte progenitor cells.It also regulates bone metabolism, inhibits production of proinflammatory cytokines and protects against gastromucosal injury.Recombinant Murine IL-11 is a 19.1kD protein consisting of 179 amino acid residues.
Catalog #143382
Biological ActivityThe ED50 was determined by the dose-dependent stimulation of the proliferation of murine T11 cells is ~2.0ng/ml, corresponding to a specific activity of ~5x10e5 units/mg.
AA SequenceMPGPPAGSPRVSSDPRADLDSAVLLTRSLLADTRQLAAQMRDKFPADGDHSLDSLPTLAMSAGTLGSLQLPGVLTRLRVDLMSYLRHVQWLRRAGGPSLKTLEPELGALQARLERLLRRLQLLMSRLALPQAAPDQPVIPLGPPASAWGSIRAAHAILGGLHLTLDWAVRGLLLLKTRL
Quality ControlVerified by N-terminal and Mass Spectrometry analyses (when applicable).
Endotoxin<0.1ng/ug of protein (<1EU/ug).
Protein ContentVerified by UV Spectroscopy and/or SDS-PAGE gel.
Storage and StabilityStore lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein.
SourceE. coli
Purity98% by SDS-PAGE gel and HPLC analyses.
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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