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You are here:Home » Growth Factors, Cytokines » Growth Factors-Interleukin » IL-15, Recombinant, Rat (IL-T)

IL-15, Recombinant, Rat (IL-T)

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Specifications

IL-15 is an immunomodulating cytokine that stimulates the proliferation of T lymphocytes and shares many biological properties with IL-2.IL-15 exerts its biological activites primarily on T cells.It is also essential in the development, survival and activation of NK cells.Increased expression of IL-15 has been implicated with rheumatoid arthritis, inflammatory bowl disease and diseases affiliated with retroviruses HIV and HTLV-I.Human IL-15 is biologically active on mouse cells as measured by the dose-dependent stimulation of the proliferation of mouse CTLL cells.Recombinant rat IL-15 is a 13.5kD protein consisting of 115 amino acid residues.
Catalog #143386
Biological ActivityThe ED50 as determined by the dose-dependant stimulation of the proliferation of murine CTLL-2 cells is ~10ng/ml, corresponding to a specific activity of ~1x10e5 units/mg.
AA SequenceMNWIDVRYDL EKIESLIQFI HIDTTLYTDS DFHPSCKVTA MNCFLLELQV ILHEYSNMTL NETVRNVLYL ANSTLSSNKN VIESGCKECE ELEERNFTEF LQSFIHIVQM FINTS
CrossreactivityHuman, Mouse
Quality ControlVerified by N-terminal and Mass Spectrometry analyses (when applicable).
Endotoxin<0.1ng/ug of protein (<1EU/ug).
Protein ContentVerified by UV Spectroscopy and/or SDS-PAGE gel.
Storage and StabilityStore lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein.
SourceE. coli
Purity98% by SDS-PAGE gel and HPLC analyses.
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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