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You are here:Home » Growth Factors, Cytokines » Growth Factors-Interleukin » IL-17B, Recombinant, Human (IL20, NIRF)

IL-17B, Recombinant, Human (IL20, NIRF)

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Specifications

IL-17B is a disulfide-linked homodimer of two 161 amino acid polypeptide chains.It belongs to the IL-17 family of structurally-related cytokines that share a highly conserved C-terminal region but differ from one another in their N-terminal regions and in their distinct biological roles.The six known members of this family, IL-17A through IL-17F, are secreted as homodimers.IL-17B is expressed by T-cells and has been shown to stimulate release of TNF-alpha and IL-1beta from cells of the monocyte lineage.Recombinant human IL-17B is a 36.6kD non-disulfide-linked homodimer of two 161 amino acid polypeptide chains.
Catalog #143388
Biological ActivityDetermined by its ability to induce IL-8 in human PBMCs using a concentration range of 10ng-100ng.
Note: Results may vary with PBMC donors.
AA SequenceMQPRSPKSKR KGQGRPGPLA PGPHQVPLDL VSRMKPYARM EEYERNIEEM VAQLRNSSEL AQRKCEVNLQ LWMSNKRSLS PWGYSINHDP SRIPVDLPEA RCLCLGCVNP FTMQEDRSMV SVPVFSQVPV RRRLCPPPPR TGPCRQRAVM ETIAVGCTCI F
Quality ControlVerified by N-terminal and Mass Spectrometry analyses (when applicable).
Endotoxin<0.1ng/ug of protein (<1EU/ug).
Protein ContentVerified by UV Spectroscopy and/or SDS-PAGE gel.
Storage and StabilityStore lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein.
SourceE. coli
Purity98% by SDS-PAGE gel and HPLC analyses.
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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