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You are here:Home » Growth Factors, Cytokines » Growth Factors-Interleukin » IL-33, Recombinant, Mouse (NF-HEV)

IL-33, Recombinant, Mouse (NF-HEV)

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Specifications

IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family.It binds and signals through the IL-1RL1/ST2 receptor activating NF-kappaB and MAP kinases.IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities. Recombinant murine IL-33 is a 17.5kD protein containing 158 amino acid residues.
Catalog #143403
Biological ActivityThe ED50 was determined by the dose-dependent stimulation of the proliferation of murine D10S cells is ~0.5ng/ml, corresponding to a specific activity of ~2x10e6units/mg.
AA SequenceSIQGTSLLTQSPASLSTYNDQSVSFVLENGCYVINVDDSGKDQEQDQVLLRYYESPCPASQSGDGVDGKKLMVNMSPIKDTDIWLHANDKDYSVELQRGDVSPPEQAFFVLHKKSSDFVSFECKNLPGTYIGVKDNQLALVEEKDESCNNIMFKLSKI
Quality ControlVerified by N-terminal and Mass Spectrometry analyses (when applicable).
Endotoxin<0.1ng/ug of protein (<1EU/ug).
Protein ContentVerified by UV Spectroscopy and/or SDS-PAGE gel.
Storage and StabilityStore lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein.
SourceE. coli
Purity98% by SDS-PAGE gel and HPLC analyses.
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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