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You are here:Home » Molecular Biology » Growth Factors-Interferon » IP-10, Recombinant, Rat (Interferon Inducible Protein 10, CXCL10, crg-2)

IP-10, Recombinant, Rat (Interferon Inducible Protein 10, CXCL10, crg-2)

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Specifications

IP-10 is a CXC chemokine that signals through the CXCR3 receptor.IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation.Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells.Recombinant rat IP-10 is an 8.6kD protein consisting of 77 amino acids including the four conserved cysteine residues present in CXC chemokines.
Catalog #143417
Biological ActivityDetermined by its ability to chemoattract hCXCR3/HEK293 cells using a concentration range of 10.0-50.0ng/ml.
AA SequenceIPLARTVRCTCIDFHEQPLRPRAIGKLEIIPASLSCPHVEIIATMKKNNEKRCLNPESEAIKSLLKAVSQRRSKRAP
CrossreactivityHuman
Quality ControlVerified by N-terminal and Mass Spectrometry analyses (when applicable).
Endotoxin<0.1ng/ug of protein (<1EU/ug).
Protein ContentVerified by UV Spectroscopy and/or SDS-PAGE gel.
Storage and StabilityStore lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein.
SourceE. coli
Purity98% by SDS-PAGE gel and HPLC analyses.
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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