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You are here:Home » Molecular Biology » Growth Factors-MIP » MIP-3, Recombinant, Human (Macrophage Inflammatory Protein-3, CCL23, MPIF-1, Ck-beta8)

MIP-3, Recombinant, Human (Macrophage Inflammatory Protein-3, CCL23, MPIF-1, Ck-beta8)

Pricing

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Specifications

MIP-3 is a CC chemokine that signals through the CCR1 receptor.MIP-3 chemoattracts monocytes, resting T-lymphocytes and neutrophils, but does not chemoattract activated lymphocytes.Additionally, MIP-3 has been shown to inhibit colony formation of bone marrow myeloid immature progenitors.Recombinant human MIP-3 is an 11.3kD protein containing 99 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Catalog #143438
Biological ActivityDetermined by its ability to chemoattract human T cell population using a concentration of 10-50ng/ml.
AA SequenceRVTKDAETEF MMSKLPLENP VLLDRFHATS ADCCISYTPR SIPCSLLESY FETNSECSKP GVIFLTKKGR RFCANPSDKQ VQVCMRMLKL DTRIKTRKN
Quality ControlVerified by N-terminal and Mass Spectrometry analyses (when applicable).
Endotoxin<0.1ng/ug of protein (<1EU/ug).
Protein ContentVerified by UV Spectroscopy and/or SDS-PAGE gel.
Storage and StabilityStore lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein.
SourceE. coli
Purity98% by SDS-PAGE gel and HPLC analyses.
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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