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You are here:Home » Growth Factors, Cytokines » Growth Factors-MIP » MIP-3 , Recombinant, Mouse (Macrophage Inflammatory Protein-3beta, CCL19, ELC, Exodus-3)

MIP-3 , Recombinant, Mouse (Macrophage Inflammatory Protein-3beta, CCL19, ELC, Exodus-3)

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Specifications

MIP-3beta is a CC chemokine that is expressed in the thymus, lymph nodes and in activated bone marrow stromal cells and signals through the CCR7 receptor.MIP-3beta is a chemoattractant for T and B lymphocytes and myeloid progenitor cells.Human MIP-3beta is active on murine cells.Recombinant murine MIP-3beta is a 9.2kD protein containing 83 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Catalog #143439
Biological ActivityDetermined by its ability to chemoattract human mature dendritic cells using a concentration range of 10.0-100.0ng/ml.
AA SequenceGANDAEDCCL SVTQRPIPGN IVKAFRYLLN EDGCRVPAVV FTTLRGYQLC APPDQPWVDR IIRRLKKSSA KNKGNSTRRS PVS
CrossreactivityHuman
Quality ControlVerified by N-terminal and Mass Spectrometry analyses (when applicable).
Endotoxin<0.1ng/ug of protein (<1EU/ug).
Protein ContentVerified by UV Spectroscopy and/or SDS-PAGE gel.
Storage and StabilityStore lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein.
SourceE. coli
Purity98% by SDS-PAGE gel and HPLC analyses.
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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