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You are here:Home » Molecular Biology » Growth Factors-Platelet Factor » PF-4, Recombinant, Human (Platelet Factor-4, CXCL4, Oncostatin A, Ironplact)

PF-4, Recombinant, Human (Platelet Factor-4, CXCL4, Oncostatin A, Ironplact)

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Specifications

PF-4 is a CXC chemokine that is expressed in megakaryocytes and stored in the alpha-granules of platelets.PF-4 is chemotactic towards neutrophils and monocytes and has been shown to inhibit angiogenesis.Recombinant human PF-4 is a 7.8kD protein containing 70 amino acid residues, including the four highly conserved residues present in CXC chemokines.
Catalog #143469
Biological ActivityDetermined by its ability to chemoattract human fibroblasts using a concentration range of 1.0-10.0ng/ml.
AA SequenceEAEEDGDLQC LCVKTTSQVR PRHITSLEVI KAGPHCPTAQ LIATLKNGRK ICLDLQAPLY KKIIKKLLES
Quality ControlVerified by N-terminal and Mass Spectrometry analyses (when applicable).
Endotoxin<0.1ng/ug of protein (<1EU/ug).
Protein ContentVerified by UV Spectroscopy and/or SDS-PAGE gel.
Storage and StabilityStore lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein.
SourceE. coli
Purity98% by SDS-PAGE gel and HPLC analyses.
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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