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You are here:Home » Molecular Biology » Growth Factors-Placenta, PlGF » PlGF-2, Recombinant, Human (Placenta Growth Factor-2, PGFL)

PlGF-2, Recombinant, Human (Placenta Growth Factor-2, PGFL)

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Specifications

PLGF-2 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors.PLGF-2 is expressed in umbilical vein endothelial cells and placenta.It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration.PlGF-2 also signals through Neuropilin (NP-1) and can bind with high affinity to heparin. Recombinant human PLGF-2 is a 34.0kD disulfide-linked homodimeric protein of two 150 amino acid polypeptide chains.
Catalog #143472
Biological ActivityDetermined by its ability to chemoattract human monocytes of using a concentration range of 5.0-50.0ng/ml.
AA SequenceLPAVPPQQWALSAGNGSSEVEVVPFQEVWGRSYCRALERLVDVVSEYPSEVEHMFSPSCVSLLRCTGCCGDENLHCVPVETANVTMQLLKIRSGDRPSYVELTFSQHVRCECRPLREKMKPERRRPKGRGKRRREKQRPTDCCGDAVPRR
Quality ControlVerified by N-terminal and Mass Spectrometry analyses (when applicable).
Endotoxin<0.1ng/ug of protein (<1EU/ug).
Protein ContentVerified by UV Spectroscopy and/or SDS-PAGE gel.
Storage and StabilityStore lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein.
SourceE. coli
Purity95% by SDS-PAGE gel and HPLC analyses.
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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