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You are here:Home » Molecular Biology » Growth Factors-SDF » SDF-1 , Recombinant, Human (Stromal Cell Derived Factor-1, CXCL12, PBSF)

SDF-1 , Recombinant, Human (Stromal Cell Derived Factor-1, CXCL12, PBSF)

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Specifications

SDF-1alpha and beta are stromal derived CXC chemokines, and signal through the CXCR4 receptor.SDF-1alpha and beta chemoattract B and T cells, and have been shown to induce migration of CD34+ stem cells.Additionally, the SDF-1 proteins exert HIV suppressive activity in cells expressing the CXCR4 receptor.Recombinant human SDF-1alpha is an 8.0kD protein containing 68 amino acid residues.
Catalog #143495
Biological ActivityDetermined by its ability to chemoattract human peripheral T cells activated with PHA and IL-2 using a concentation of 20-80ng/ml.
AA SequenceKPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKNNNRQVC IDPKLKWIQE YLEKALNK
CrossreactivityMouse, Rat
Quality ControlVerified by N-terminal and Mass Spectrometry analyses (when applicable).
Endotoxin<0.1ng/ug of protein (<1EU/ug).
Protein ContentVerified by UV Spectroscopy and/or SDS-PAGE gel.
Storage and StabilityStore lyophilized products at -20°C. For reconstituted solutions of most products, we recommend short-term storage at 4°C. For longer term storage the protein solution should be stored with a carrier protein (eg. 0.1% BSA) in working aliquots and stored frozen at -20°C. Additional freeze/thaw cycles may cause some denaturation of the protein.
SourceE. coli
Purity98% by SDS-PAGE gel and HPLC analyses.
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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