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You are here:Home » Antibodies » Abs to Receptors, Cholinergic » Anti -CHRM1 (acetylcholine receptor, muscarinic 1, Muscarinic acetylcholine receptor M1)

Anti -CHRM1 (acetylcholine receptor, muscarinic 1, Muscarinic acetylcholine receptor M1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
Muscarinic acetylcholine receptor M1, also known as cholinergic receptor, muscarinic 1, is a muscarinic receptor. This gene is mapped to 11q12.3. The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 1 is involved in mediation of vagally-induced bronchoconstriction and in the acid secretion of the gastrointestinal tract.
Catalog #144366
UniProt NumberP11229
Gene IDCHRM1
ApplicationsSuitable for use in Western Blot and Immunohistochemistry (Paraffin).
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and HandlingStore at -20 C for one year. After reconstitution, store at 4 C for one month. Can also be aliquoted and stored frozen at -20 C for long term.
Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide corresponding to a sequence at the C-terminus of human CHRM1, identical to the related mouse sequence, and different from the related rat sequence by one amino acid.
SpecificityRecognizes human, mouse and rat CHRM1. No crossreactivity with other proteins.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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