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You are here:Home » Antibodies » Abs to Keratin, Cytokeratin » Anti -CK-19/KRT19 (Cytokeratin-19)

Anti -CK-19/KRT19 (Cytokeratin-19)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH IC
Keratin, type I cytoskeletal 19 is a protein that in humans is encoded by the KRT19 gene.The protein encoded by this gene is a member of the keratin family. It is specifically expressed in the periderm, the transiently superficial layer that envelops the developing epidermis. The type I cytokeratins are clustered in a region of chromosome 17q12-q21. Due to its high sensitivity, KRT19 is the most used marker for the RT-PCR-mediated detection of tumor cells disseminated in lymph nodes, peripheral blood, and bone marrow of breast cancer patients.Keratin 19 is often used together with keratin 8 and keratin 18 to differentiate cells of epithelial origin from hematopoietic cells in tests that enumerate circulating tumor cells in blood.
Catalog #144369
UniProt NumberP08727
Gene IDKRT19
ApplicationsSuitable for use in Western Blot, Immunohistochemistry (Paraffin) and Immunocytochemistry.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and HandlingStore at -20 C for one year. After reconstitution, store at 4 C for one month. Can also be aliquoted and stored frozen at -20 C for long term.
Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide corresponding to a sequence at the C-terminal of human CK19.
SpecificityRecognizes human CK-19/KRT19. No crossreactivity with other proteins.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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