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You are here:Home » Antibodies » Abs to Glucose Transporters » Anti -FLOT2 (ESA1, M17S1, ESA, ECS-1, Epidermal surface antigen, Membrane component chromosome 17 surface marker 1, membrane component, chromosome 17, surface marker 1 (35kD protein identified by monoclonal antibody ECS-1))

Anti -FLOT2 (ESA1, M17S1, ESA, ECS-1, Epidermal surface antigen, Membrane component
chromosome 17 surface marker 1, membrane component, chromosome 17, surface marker 1 (35kD
protein identified by monoclonal antibody ECS-1))

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
FLOT2 (Flotillin 2), also known as ESA1 or M17S1, is a protein that in humans is encoded by the FLOT2 gene. Schroeder et al. (1991) isolated a cDNA for an epidermal surface antigen believed to be involved in epidermal cell adhesion. By analysis of a somatic cell hybrid panel and in situ hybridization using the ESA cDNA, the gene was mapped to 17q11-q12 in the region containing the NF1 gene. Bickel et al. (1997) found that mouse Flot2 consistently copurifies with Flot1 and with caveolin-1 in the purification of caveolin-rich membranes. Using a quantitative proteomic analysis of cultured mouse neuronal stem cells, Li et al. (2012) found that palmitoylation and oligomerization of flotillin-2 was abolished in homozygous Dhhc5 mutant neuronal stem cells. The absolute amount of flotillin-2 was not changed in Dhhc5 mutant neurons.
Catalog #144539
UniProt NumberQ14254
Gene IDFLOT2
ApplicationsSuitable for use in Western Blot.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and HandlingStore at -20 C for one year. After reconstitution, store at 4 C for one month. Can also be aliquoted and stored frozen at -20 C for long term.
Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a lyophilized powder. Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3. Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide corresponding to a sequence at the N-terminal of human FLOT2, identical to the related rat and mouse sequences.
SpecificityRecognizes human,mouse and rat FLOT2. No crossreactivity with other proteins.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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