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144849 Rabbit Anti-AQP9 (m.AQP9, HsT17287, SSC1, Aquaglyceroporin-9)

Specifications
References
Clone Type
Polyclonal
Host
Rabbit
Source
Mouse
Swiss Prot
Q9JJJ3
Isotype
IgG
Grade
Affinity Purified
Applications
WB
Crossreactivity
Mo
Gene ID
AQP9
Shipping Temp
Blue Ice
Storage Temp
-20°C

Aquaporin-9 is a protein that in humans is encoded by the AQP9 gene. AQP9 encodes a 295-amino-acid protein with the amino acid sequence identity with AQP3 (48%), AQP7 (45%), and other aquaporins (approximately 30%), suggesting that AQP3, AQP7, and AQP9 belong to a subfamily of the aquaporin family. AQP9 is the major glycerol channel in mouse erythrocytes and suggest that this transport pathway may contribute to the virulence of intraerythrocytic stages of malarial infection.

UniProt Number
Q9JJJ3
Gene ID
AQP9
Applications
Suitable for use in Western Blot. Other applications not tested.
Recommended Dilution
Optimal dilutions to be determined by the researcher.
Storage and Stability
Lyophilized and reconstituted products are stable for 12 months after receipt at -20°C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Immunogen
A synthetic peptide corresponding to a sequence at the C-terminal of mouse AQP9
Form
Supplied as a lyophilized powder from PBS, 5% BSA, 0.05% Thimerosal, 0.05% sodium azide. Reconstitutie with 200ul sterile ddH2O.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes mouse m.AQP9. No crossreactivity with other proteins.
References
1. "Entrez Gene: AQP9 aquaporin 9"|2. Ishibashi, K., Kuwahara, M., Gu, Y., Tanaka, Y., Marumo, F., Sasaki, S. Cloning and functional expression of a new aquaporin (AQP9) abundantly expressed in the peripheral leukocytes permeable to water and urea, but not to glycerol. Biochem. Biophys. Res. Commun. 244: 268-274, 1998. |3. Liu, Y., Promeneur, D., Rojek, A., Kumar, N., Frokiaer, J., Nielsen, S., King, L. S., Agre, P., Carbrey, J. M. Aquaporin 9 is the major pathway for glycerol uptake by mouse erythrocytes, with implications for malarial virulence. Proc. Nat. Acad. Sci. 104: 12560-12564, 2007.|
USBio References
No references available
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