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You are here:Home » Antibodies » Abs to Paxillin » Anti -Paxillin (PAX)

Anti -Paxillin (PAX)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites B IC
The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68-kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells.
Catalog #145032
UniProt NumberHuman(P49023), Mouse(Q8VI36), Rat(Q66H76)
Gene IDPXN
ApplicationsSuitable for use in Western Blot and Immunocytochemistry.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and HandlingStore at -20 C for one year. After reconstitution, store at 4 C for one month. Can also be aliquoted and stored frozen at -20 C for long term.
Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone NoPAX-14
HostMouse
SourceChicken
Concentration~0.1mg/ml
FormAscites, supplied as a lyophilized powder. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
ImmunogenC-terminal part of recombinant chicken paxillin (amino acids 305-559).
SpecificityRecognizes human, mouse, rat and chicken Paxillin. No crossreactivity with other proteins.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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