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You are here:Home » Antibodies » Abs to Spectrin » Anti -Spectrin (alpha and beta) (EL2, HPP, HS3, SPH3, SPTA, EL3, HS2, SPH2, HSPTB1, Erythroid alpha-spectrin)

Anti -Spectrin (alpha and beta) (EL2, HPP, HS3, SPH3, SPTA, EL3, HS2, SPH2, HSPTB1,
Erythroid alpha-spectrin)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Ascites B
Spectrin, the predominant component of the membrane skeleton of the red cell, is essential in determining the properties of the membrane including its shape and deformability. It consists of 2 nonidentical subunits, alpha and beta. Spectrin is present in the red cell membrane in a tetrameric or possibly higher polymeric form through head-to-head self-association of heterodimers that are linked by actin polymers and protein 4.1 to form a 2-dimensional network. Non-erythroid spectrin gene is mapped to human chromosome 2.Spectrin mutations cause spinocerebellar ataxia type 5.
Catalog #145214
UniProt NumberHuman(P02549), Mouse(P08032), Rat(D4A678), Human(P11277), Mouse(P15508), Rat(Q6XDA0)
Gene IDSPTA1; SPTB
ApplicationsSuitable for use in Western Blot.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and HandlingStore at -20 C for one year. After reconstitution, store at 4 C for one month. Can also be aliquoted and stored frozen at -20 C for long term.
Avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone NoSpe 1/2
HostMouse
SourceHuman
Concentration~0.1mg/ml
FormAscites, supplied as a lyophilized powder. Reconstitution: 1.2% sodium acetate or neutral PBS. If 1ml of PBS is used, the antibody concentration will be 100ug/ml.
ImmunogenHuman erythrocyte spectrin.
SpecificityRecognizes human Spectrin(alpha and beta). No crossreactivity with other proteins.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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