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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -Allergin-1 (Allergy Inhibitory Receptor 1, C17orf60, MCA32, Mast Cell Antigen, MCA32-1S2, MILR1) (APC)

Anti -Allergin-1 (Allergy Inhibitory Receptor 1, C17orf60, MCA32, Mast Cell Antigen,
MCA32-1S2, MILR1) (APC)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
Allergin-1, also known as Mast Cell Antigen (MCA32) and c17orf60, is a 70kD member of the Ig superfamily. It is expressed on mast cells, basophils, neutrophils, and macrophages, and is reported to negatively regulate allergic mediator release from mast cells. In particular, Allergin-1 interacts with FcepsilonRI. Upon IgE-mediated FcepsilonRI aggregation and activation, Allergin-1 recruits Tyr phosphatases to FcepsilonRI tetrameric complexes, dampening IgE receptor downstream signaling.
Catalog #145385
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 10ul, 1x10e6 cells
Optimal dilutions to be determined by the researcher.
HybridomaMouse myeloma cells with B cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at 12 months at 4°C. Freezing allophycocyanin conjugates will result in a substantial loss of activity. Allophycocyaninconjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG1
Clone No767727
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant protein corresponding to aa1-127 from human Allergin, NS0-derived.
SpecificityRecognizes human Allergin-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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