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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -BAFF (BLyS, CD257, TALL1, THANK, TNFSF13B, ZTNF4) (APC)

Anti -BAFF (BLyS, CD257, TALL1, THANK, TNFSF13B, ZTNF4) (APC)

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified FC
BAFF (also known as TALL1, BLyS, and THANK) is a type II transmembrane glycoprotein belonging to the TNF superfamily and has been designated TNF superfamily member 13B (TNFSF13B). Mouse BAFF is a 309 amino acid (aa) protein consisting of a 248aa extracellular domain, a 21aa transmembrane region and a 45 aacytoplasmic tail.1, 2 BAFF has the typical structural characteristics of TNF superfamily ligands. It is a homotrimeric protein having the structurally conserved motif known as TNF homology domain.3, 4 BAFF is expressed in peripheral blood mononuclear cells, in spleen and lymph nodes. Its expression in resting monocytes is up-regulated by IFN-alpha, IFN-beta, LPS, and IL-10. BAFF provides critical survival signals to a subset of B cells with intermediate maturation status (T2 B cells) during the immune response.
Catalog #145398
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 10ul, 1x10e6 cells
Optimal dilutions to be determined by the researcher.
HybridomaMouse myeloma cells with B cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at 12 months at 4°C. Freezing allophycocyanin conjugates will result in a substantial loss of activity. Allophycocyaninconjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No121808
HostRat
SourceMouse
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
PurityPurified by Protein A or G affinity chromatography.
ImmunogenRecombinant protein corresponding to aa127-309 from mouse BAFF, NS0-derived (rmBAFF; Accession # Q9WU72).
SpecificityRecognizes mouse BAFF.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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