Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Cadherin » Anti -CDH1 (E-Cadherin, Arc-1, CAD1, Cadherin-1, CD324, Cell-CAM120/80, ECAD, L-CAM, Uvomorulin) (PerCP)

Anti -CDH1 (E-Cadherin, Arc-1, CAD1, Cadherin-1, CD324, Cell-CAM120/80, ECAD, L-CAM,
Uvomorulin) (PerCP)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
Epithelial (E)-Cadherin (ECAD), also known as Cadherin-1, cell- CAM120/80 in human, Uvomorulin in mouse, Arc1 in dog, and LCAM in chicken, is a member of the Cadherin family of cell adhesion molecules (gene name CDH1). Cadherins are calcium-dependent transmembrane proteins that bind to one another in a homophilic manner. E-Cadherin may play a role in tumor development, as loss of E-Cadherin has been associated with tumor invasiveness. E- Cadherin is a classical cadherin molecule. Classical cadherins consist of a large extracellular domain which contains DXD and DXNDN repeats responsible for mediating calcium-dependent adhesion, a single-pass transmembrane domain, and a short carboxy-terminal cytoplasmic domain responsible for interacting with the catenins. E-Cadherin contains five extracellular calcium-binding domains of ~110 amino acids each (amino acids 155-697).
Catalog #145429
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 10ul, 1x10e6 cells
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. PerCP conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No180224
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.5% BSA, 0.09% sodium azide. Labeled with PerCP.
PurityPurified by Protein A or G affinity chromatography.
ImmunogenRecombinant protein corresponding to aa155-707 from human E-Cadherin, NS0-derived (Accession# P12830).
SpecificityRecognizes human E-Cadherin.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links