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You are here:Home » Antibodies » Abs to Blood Groups » Anti -ERMAP (Erythrocyte Membrane-associated Protein, Scianna Blood Group Antigen, RD, SC) (APC)

Anti -ERMAP (Erythrocyte Membrane-associated Protein, Scianna Blood Group Antigen, RD, SC)
(APC)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
ERMAP (erythrocyte membrane-associated protein; also known as Scianna blood group antigen) is a 6066kD member of the BTN/MOG family, Ig superfamily of proteins. It is expressed on erythrocytes and erythrocyte precursors and likely serves as a cell adhesion molecule. Mature human ERMAP is a 446 amino acid (aa) type I transmembrane glycoprotein. It possesses a 126 aaextracellular domain (ECD; aa30-155) that contains one V-type Ig-like domain (aa30-140). Single aachanges at Gly35, Glu47, Gly57, Pro60, and Arg81 generate distinct antigens of the Scianna blood group. There is one alternate start site at Met91 and a splice variant that shows an 11aa substitution for aa103-475. Over aa30-155, human ERMAP is 56% aa identical to mouse ERMAP. In contrast to the extracellular domain of human ERMAP, the ECD of mouse ERMAP contains one extra Ig-like domain.
Catalog #145459
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 10ul, 1x10e6 cells
Optimal dilutions to be determined by the researcher.
HybridomaMouse myeloma cells with B cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for at 12 months at 4°C. Freezing allophycocyanin conjugates will result in a substantial loss of activity. Allophycocyaninconjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG1
Clone No767505
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
PurityPurified by Protein A or G affinity chromatography.
ImmunogenRecombinant protein corresponding to aa30-155 from human ERMAP, NS0-derived (rhERMAP; Accession # Q96PL5).
SpecificityRecognizes human ERMAP.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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