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You are here:Home » Antibodies » Abs to PDZ Domain » Anti -FRMPD4 (PDZD10, PDZK10, Preso)

Anti -FRMPD4 (PDZD10, PDZK10, Preso)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B
Preso, also known as FRMPD4 and PDZD10, is a scaffolding protein that is widely expressed in the brain as 140kD and 170kD species. It contains one WW domain (aa33­66) one PDZ domain (aa78­155), and one FERM domain (aa 204­519). The 140kD species is enriched in post­synaptic densities where it interacts with PSD­95, SAP97, SAP102, and F­actin. Preso promotes dendritic spine extension and maintenance as well as excitatory synaptic transmission. Within aa890­1022, human Preso shares ~94% aa sequence identity with mouse and rat Preso.
Catalog #145468
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 2ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No809408
HostMouse
SourceHuman
Concentration~0.5mg/ml (after reconstitution)
FormSupplied as a lyophilized powder in PBS, Trehalose. Reconstitute in sterile PBS.
PurityPurified by Protein A or G affinity chromatography.
ImmunogenRecombinant protein corresponding to aa890-1022 from human Preso/FRMPD4, expressed in E. coli (Accession# Q14CM0).
SpecificityRecognizes human Preso/FRMPD4 in direct ELISAs and human and mouse Preso/FRMPD4 in Western blots.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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