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You are here:Home » Antibodies » Abs to Cell Surface Proteins » Anti -Ly6K (Lymphocyte Antigen 6 Locus K, CO16, CT97)

Anti -Ly6K (Lymphocyte Antigen 6 Locus K, CO16, CT97)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E FC
Ly6K (Lymphocyte antigen 6 locus K; also CO16) is a 26-27kD member of the Ly-6 antigen family of molecules. It has restricted expression, being described in testis and skin. Ly6K is found in/on carcinomas, and is known to circulate in normal and tumor-patient blood. Mature human Ly6K is a 121 amino acid (aa) GPI-linked (presumed) glycoprotein. It is synthesized as a 165aa preproprecursor that contains a 17aa signal sequence, a 121aa mature region (aa18-138), and a 27aa C-terminal propeptide. There are two potential splice variants, one that shows a 48 aa substitution, and another that shows a 33aa substitution for aa73-165. It is not clear if mouse Ly6K is a true molecular ortholog of human Ly6K. In any event, over aa18-138, human Ly6K shares 39% aa identity with mouse Ly6K.
Catalog #145516
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 2.5ug/10e6 cells
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No750747
HostMouse
SourceHuman
Concentration~0.5mg/ml (after reconstitution)
FormSupplied as a lyophilized powder in PBS, Trehalose. Reconstitute in sterile PBS.
PurityPurified by Protein A or G affinity chromatography.
ImmunogenRecombinant protein corresponding to aa1-138 from human Ly6K, CHO-derived (Accession# Q17RY6).
SpecificityRecognizes human Ly6K in direct ELISAs.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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