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You are here:Home » Antibodies » Abs to Mucin » Anti -MUC-1 (Episialin, H23AG, KL-6, Mucin-1, PEM, PEMT) Tumor-associated Mucin, Carcinoma-associated Mucin)

Anti -MUC-1 (Episialin, H23AG, KL-6, Mucin-1, PEM, PEMT) Tumor-associated Mucin,
Carcinoma-associated Mucin)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
MUC-1 (Mucin-1; also known as PEM, PEMT, Episialin, tumor- associated mucin, and carcinoma-associated mucin) is a 240-450kD type I transmembrane glycoprotein. Human MUC-1 is 1255 amino acids (aa) in length and contains a 23 aa signal sequence, a 1135 aa extracellular domain (ECD), a 23 aa transmembrane segment, and a 74 aa cytoplasmic tail. The ECD consists of degenerate tandem repeats and a tandem repeat region, which makes up the major portion of the protein. Potential O-glycosylation sites (serines and threonines) make up more than one-fourth of the amino acids. Splicing variations produce ten different isoforms of human MUC-1. Human MUC-1 is 28% aa identical to mouse MUC-1.
Catalog #145534
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 10ul, 1x10e6 cells
Optimal dilutions to be determined by the researcher.
HybridomaMouse myeloma cells with B cells from Balb/c mice.
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No604804
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.5% BSA, 0.09% sodium azide. Labeled with R-Phycoerythrin (PE).
PurityPurified by Protein A or G affinity chromatography.
ImmunogenRecombinant protein corresponding to aa126-145 from human MUC-1, expressed in E. coli (Accession# P15941).
SpecificityRecognizes human MUC-1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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