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You are here:Home » Antibodies » Abs to Mitosis Proteins » Anti -MARVELD1 (MARVEL Domain-containing Protein 1, MRVLDC1, bA548K23.8, FLJ22343, FLJ23440, GB14, MARVD1, MGC4415, RP11-548K23.8)

Anti -MARVELD1 (MARVEL Domain-containing Protein 1, MRVLDC1, bA548K23.8, FLJ22343,
FLJ23440, GB14, MARVD1, MGC4415, RP11-548K23.8)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B
MARVELD1, (MARVEL domain-containing 1), is one of the MARVEL (MAL and related proteins for vesicle trafficking and membrane link) domain-containing proteins. It is a nuclear-localized protein that is widely expressed in normal human tissues. While it has been reported to be overexpressed in colon cancer, MARVELD1 protein levels are generally lower in several primary tumors including ovary, breast, kidney, bladder and liver. This lower level of MARVELD1 expression in tumors is thought to be due to a higher methylation status of the MARVELD1 promoter as treatment of MDA-MB-361 with 5-aza-2'-deoxycytidine restores MARVELD1 expression (1,3), suggesting that loss of MARVELD1 expression may contribute to tumorgenicity.
Catalog #146554
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlMouse Heart Tissue Lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to 16aa from near the N-terminus of human MARVELD1.
SpecificityRecognizes human MARVELD1. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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