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You are here:Home » Antibodies » Abs to G Proteins » Anti -ARHGAP18 (Rho GTPase-activating Protein 18, MacGAP, Rho-type GTPase-activating Protein 18, bA307O14.2, FLJ25728, MacGAP, MGC126757, MGC138145)

Anti -ARHGAP18 (Rho GTPase-activating Protein 18, MacGAP, Rho-type GTPase-activating
Protein 18, bA307O14.2, FLJ25728, MacGAP, MGC126757, MGC138145)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IC IF
ARHGAP18 is one member of the human RhoGAP family with approximately 80 RhoGAP proteins known to be encoded in the human genome. Rho proteins belong to the Ras superfamily that is composed of over 50 members divided into six families, including Ras, Sar, Rho, Ran, Rab and Arf. Rho GTPases are important regulators of the actin cytoskeleton and consequently influence the shape and migration of cells. ARHGAP18 is linked to Ras, and thus, to EGFR-mediated proliferation, migration and differentiation. ARHGAP18 is precisely contained within chromosome 6q22-24, which has been shown to be linked to schizophrenia, suggesting that ARHGEP18 may play a role in this condition.
Catalog #146591
ApplicationsSuitable for use in Immunofluorescence, ELISA, Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml
Optimal dilutions to be determined by the researcher.
Positive Control3T3 (NIH) Cell Lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to 15aa from near the C-terminus of human ARHGAP18.
SpecificityRecognizes human ARHGAP18. Species Crossreactivity: mouse and rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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