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You are here:Home » Antibodies » Abs to Enzymes, ATPase » Anti -ATP11B (Probable Phospholipid-transporting ATPase IF, ATPase IR, ATPase Class VI Type 11B, ATPIF, ATPIR, KIAA0956)

Anti -ATP11B (Probable Phospholipid-transporting ATPase IF, ATPase IR, ATPase Class VI
Type 11B, ATPIF, ATPIR, KIAA0956)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IC IF
ATP11B is a widely expressed integral membrane ATPase and is thought to drive the transport of phospholipids across membranes. It has been suggested that ATP11B is hormonally regulated and plays a role in the subnuclear trafficking of transcription factors with RING motifs. While the exact molecule ATP11B transports is unknown, increased mRNA expression of the homologous ATP11A has been observed in cells resistant to anti-cancer drugs such as farnesyltransferase inhibitors (FTIs), suggesting that ATP11B may also play a role in cell survival under harsh conditions.
Catalog #146699
ApplicationsSuitable for use in ELISA, Western Blot, Immunofluorescence and Immunocytochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1ug/ml
Immunocytochemistry: 10ug/ml
Immunofluorescence: 20ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlK562 Cell Lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to 19aa from near the N-terminus of human ATP11B.
SpecificityRecognizes human ATP11B. Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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