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You are here:Home » Molecular Biology » Growth Factors-Placenta, PlGF » PlGF-1, Recombinant, Human (Placenta Growth Factor-1, PIGF, PGF)

PlGF-1, Recombinant, Human (Placenta Growth Factor-1, PIGF, PGF)

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Specifications

PlGF-1 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-1 is expressed in placental tissues, colon and mammary carcinomas. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. Recombinant human PlGF-1 is a 29.7kD disulfide-linked homodimeric protein of two 131aa polypeptide chains.
Catalog #149575
SourceRecombinant protein corresponding to human PlGF-1, expressed in E. coli.
Biological ActivityDetermined by its ability to chemoattract human monocytes of using a concentration range of 1-10ng/ml.
Endotoxin<0.1ng/ug (1EU/ug)
AA SequenceMLPAVPPQQW ALSAGNGSSE VEVVPFQEVW GRSYCRALER LVDVVSEYPS EVEHMFSPSC VSLLRCTGCC GDENLHCVPV ETANVTMQLL KIRSGDRPSY VELTFSQHVR CECRPLREKM KPERCGDAVP RR
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~95% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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