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You are here:Home » Molecular Biology » Growth Factors-Placenta, PlGF » PlGF-3, Recombinant, Human (Placenta Growth Factor-3, PGFL)

PlGF-3, Recombinant, Human (Placenta Growth Factor-3, PGFL)

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Specifications

PlGF-3 is an angiogenic factor that belongs to the cysteine-knot superfamily of growth factors. PlGF-3 is expressed exclusively in the placenta. It signals through the VEGFR-1/FLT1 receptor and stimulates endothelial cell proliferation and migration. PlGF-3 lacks heparin binding affinity. Recombinant human PlGF-3 is a 45.7kD disulfide-linked homodimeric protein of two 203aa polypeptide chains.
Catalog #149596
SourceRecombinant protein corresponding to human PlGF-3, expressed in E. coli.
Biological ActivityDetermined by its ability to chemoattract human monocytes using a concentration range of 5-50ng/ml.
Endotoxin<0.1ng/ug (1EU/ug)
AA SequenceLPAVPPQQWA LSAGNGSSEV EVVPFQEVWG RSYCRALERL VDVVSEYPSE VEHMFSPSCV SLLRCTGCCG DENLHCVPVE TANVTMQLLK IRSGDRPSYV ELTFSQHVRC ECRHSPGRQS PDMPGDFRAD APSFLPPRRS LPMLFRMEWG CALTGSQSAV WPSSPVPEEI PRMHPGRNGK KQQRKPLREK MKPERCGDAV PRR
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~95% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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