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You are here:Home » Growth Factors, Cytokines » Growth Factors-BMP » BMP4, Recombinant, Human (Bone Morphogenetic Protein 4, BMP-4, Bone Morphogenetic Protein 2B, BMP-2B, BMP2B, DVR4, DVR4, MCOPS6, OFC11, ZYME)

BMP4, Recombinant, Human (Bone Morphogenetic Protein 4, BMP-4, Bone Morphogenetic Protein
2B, BMP-2B, BMP2B, DVR4, DVR4, MCOPS6, OFC11, ZYME)

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Specifications

Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-beta superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. Recombinant human BMP-4, expressed in HeLa cells, is a 31-36kD homodimeric glycoprotein.
Catalog #149598
SourceRecombinant protein corresponding to human BMP-4, expressed in HeLa cells.
Biological ActivityDetermined by its ability to induce alkaline phosphatase production by ATDC-5 cells.
Endotoxin<0.1ng/ug (1EU/ug)
AA SequenceHHSQRARKKN KNCRRHSLYV DFSDVGWNDW IVAPPGYQAF YCHGDCPFPL ADHLNSTNHA IVQTLVNSVN SSIPKACCVP TELSAISMLY LDEYDKVVLK NYQEMVVEGC GCR
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceHeLa cells
Purity~97% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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