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You are here:Home » Molecular Biology » Growth Factors-Interferon » IFNL1, Recombinant, Human (Interferon lambda-1, IFN-lambda-1, Cytokine Zcyto21, Interleukin-29, IL-29, IL29, ZCYTO21)

IFNL1, Recombinant, Human (Interferon lambda-1, IFN-lambda-1, Cytokine Zcyto21,
Interleukin-29, IL-29, IL29, ZCYTO21)

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Specifications

IFN lambda-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas use a distinct receptor system composed of an IFN-lambdaR1 subunit (also called CRF2-12) and IL-10R2 subunit (also called CRF2-14). Signaling through this receptor system induces antiviral defense similar but distinct than the type I Interferons. Recombinant human IFN-lamda 1 is a 19.8kD protein containing 178aa.
Catalog #149643
SourceRecombinant protein corresponding to human IFN lamda 1, expressed in E.coli.
Biological ActivityRecombinant human IFN-lambda 1 induces phosphorylation of STAT2.
Endotoxin<0.1ng/ug (1EU/ug)
AA SequencePTSKPTTTGK GCHIGRFKSL SPQELASFKK ARDALEESLK LKNWSCSSPV FPGNWDLRLL QVRERPVALE AELALTLKVL EAAAGPALED VLDQPLHTLH HILSQLQACI QPQPTAGPRP RGRLHHWLHR LQEAPKKESA GCLEASVTFN LFRLLTRDLK YVADGNLCLR TSTHPEST
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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