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You are here:Home » Molecular Biology » Growth Factors-BAFF » BAFF Receptor, Recombinant, Human (BAFFR, BAFF-R, B Cell-activating Factor Receptor, BLyS Receptor 3, BR3, BROMIX, CD268, CVID4, MGC138235, Prolixin, Tumor Necrosis Factor Receptor Superfamily Member 13C, TNFRSF13C)

BAFF Receptor, Recombinant, Human (BAFFR, BAFF-R, B Cell-activating Factor Receptor, BLyS
Receptor 3, BR3, BROMIX, CD268, CVID4, MGC138235, Prolixin, Tumor Necrosis Factor Receptor
Superfamily Member 13C, TNFRSF13C)

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Specifications

BAFF Receptor (BAFFR), a member of the TNFR superfamily, is highly expressed in spleen, lymph node, and resting B cells and to some extent in activated B cells, resting CD4+ cells and peripheral blood leukocytes. BAFFR is a type III transmembrane protein that binds with high specificity to BAFF (TNFSF13B). BAFFR/BAFF signaling plays a critical role in B cell survival and maturation. Recombinant human BAFFR is a 76aa polypeptide (7.7kD) corresponding to the extracellular portion of the full BAFFR protein.
Catalog #149654
SourceRecombinant protein corresponding to human BAFF Receptor, expressed in E.coli.
Biological ActivityDetermined by its ability to block BAFF induced mouse splenocyte survival. The expected ED50 for this effect is 2-4ug/ml in the presence of 1ug/ml of human soluble BAFF.
Endotoxin<0.1ng/ug (1EU/ug)
AA SequenceMRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPG
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~95% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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