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You are here:Home » Growth Factors, Cytokines » Growth Factors-Eotaxin » Ccl24, Recombinant, Mouse (C-C Motif Chemokine 24, Eosinophil Chemotactic Protein 2, Eotaxin-2, Small-inducible Cytokine A24, Scya24)

Ccl24, Recombinant, Mouse (C-C Motif Chemokine 24, Eosinophil Chemotactic Protein 2,
Eotaxin-2, Small-inducible Cytokine A24, Scya24)

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Specifications

Eotaxin-2 is a CC chemokine that signals through the CCR3 receptor. It is produced by activated monocytes and T lymphocytes. Eotaxin-2 selectively chemoattracts cells expressing CCR3 including eosinophils, basophils, Th2 T cells, mast cells, and certain subsets of dendritic cells. Additionally, Eotaxin-2 inhibits the proliferation of multipotential hematopoietic progenitor cells. The mature protein, which also includes a C-terminal truncation, contains 78aa (92aa residues for the murine homolog, without C-terminal truncation). Recombinant murine Eotaxin-2 is an 10.3kD protein containing 93aa.
Catalog #149678
SourceRecombinant protein corresponding to mouse Eotaxin-2, expressed in E.coli.
Biological ActivityDetermined by its ability to chemoattract murine lymphocytes using a concentration range of 10-100ng/ml.
Endotoxin<0.1ng/ug (1EU/ug)
AA SequenceVTIPSSCCTS FISKKIPENR VVSYQLANGS ICPKAGVIFI TKKGHKICTD PKLLWVQRHI QKLDAKKNQP SKGAKAVRTK FAVQRRRGNS TEV
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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