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You are here:Home » Molecular Biology » Growth Factors-LIX » CXCL5, Recombinant, Mouse (C-X-C Motif Chemokine 5, ENA-78 (1-78), Epithelial-derived Neutrophil-activating Protein 78, Neutrophil-activating Peptide ENA-78, Small-inducible Cytokine B5, ENA78, SCYB5)

CXCL5, Recombinant, Mouse (C-X-C Motif Chemokine 5, ENA-78 (1-78), Epithelial-derived
Neutrophil-activating Protein 78, Neutrophil-activating Peptide ENA-78, Small-inducible
Cytokine B5, ENA78, SCYB5)

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Specifications

The murine homolog of ENA-78 is called LIX. LIX is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. LIX is a chemoattractant for neutrophils. The two naturally occurring variants of LIX; LIX 1-78 (GCP-2) and LIX 9-78 (GCP-2), contain 78 and 70aa, respectively. LIX contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR’ motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Recombinant murine LIX is a 7.6kD protein consisting ofaa 9-78 of the full length LIX protein (93aa).
Catalog #149681
SourceRecombinant protein corresponding to mouse LIX, expressed in E.coli.
Biological ActivityDetermined by its ability to chemoattract human neutrophils using a concentration range of 10-100ng/ml.
Endotoxin<0.1ng/ug (1EU/ug)
AA SequenceTELRCVCLTV TPKINPKLIA NLEVIPAGPQ CPTVEVIAKL KNQKEVCLDP EAPVIKKIIQ KILGSDKKKA
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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