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You are here:Home » Molecular Biology » Growth Factors-CXCL » CXCL5, Recombinant, Human (C-X-C Motif Chemokine 5, ENA-78 (1-78), Epithelial-derived Neutrophil-activating Protein 78, Neutrophil-activating Peptide ENA-78, Small-inducible Cytokine B5, ENA78, SCYB5)

CXCL5, Recombinant, Human (C-X-C Motif Chemokine 5, ENA-78 (1-78), Epithelial-derived
Neutrophil-activating Protein 78, Neutrophil-activating Peptide ENA-78, Small-inducible
Cytokine B5, ENA78, SCYB5)

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Specifications

ENA-78 is a CXC chemokine that signals through the CXCR2 receptor. It is expressed in monocytes, platelets, endothelial cells, and mast cells. ENA-78 is a chemoattractant for neutrophils. The murine homolog of ENA-78 is called LIX. Three N-terminal truncated variants of human ENA-78; ENA 5-78, ENA 8-78, ENA 9-78, contain 74, 71, and 70aa, respectively, possess increased biological activity. ENA-78 contains the four conserved cysteine residues present in CXC chemokines, and also contains the 'ELR’ motif common to CXC chemokine that bind to the CXCR1 and CXCR2 receptors. Recombinant human ENA-78 is a 7.8kD protein consisting of 71aa.
Catalog #149684
SourceRecombinant protein corresponding to human ENA-78, expressed in E.coli.
Biological ActivityDetermined by its ability to chemoattract human neutrophils using a concentration range of 10-100ng/ml.
Endotoxin<0.1ng/ug (1EU/ug)
AA SequenceLRELRCVCLQ TTQGVHPKMI SNLQVFAIGP QCSKVEVVAS LKNGKEICLD PEAPFLKKVI QKILDGGNKE N
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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