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You are here:Home » Molecular Biology » Growth Factors-CCL » CCL14, Recombinant, Human (C-C Motif Chemokine 14, Chemokine CC-1/CC-3, HCC-1/HCC-3, HCC-1(1-74), NCC-2, Small-inducible Cytokine A14, NCC2, SCYA14)

CCL14, Recombinant, Human (C-C Motif Chemokine 14, Chemokine CC-1/CC-3, HCC-1/HCC-3,
HCC-1(1-74), NCC-2, Small-inducible Cytokine A14, NCC2, SCYA14)

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Specifications

HCC-1 is a CC chemokine that signals through the CCR1 receptor and chemoattracts blood monocytes. It is secreted by various tissues including skeletal muscle, heart, spleen, liver, bone marrow and plasma. Mature HCC-1 is found in four different forms, which are distinguished by differential N-terminal truncation and contain 74, 72, 71, or 66aa. Recombinant human HCC-1 (66aa) is a 7.8kD protein consisting of 66aa including the four highly conserved residues present in CC chemokines.
Catalog #149687
SourceRecombinant protein corresponding to human HCC-1, expressed in E.coli.
Biological ActivityDetermined by its ability to chemoattract human monocytes using a concentration range of 5-20ng/ml.
Endotoxin<0.1ng/ug (1EU/ug)
AA SequenceGPYHPSECCF TYTTYKIPRQ RIMDYYETNS QCSKPGIVFI TKRGHSVCTN PSDKWVQDYI KDMKEN
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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