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You are here:Home » Growth Factors, Cytokines » Growth Factors-IP-10 » IP-10, Recombinant, Rat (Cxcl10, C-X-C Motif Chemokine 10, 10kD Interferon gamma-induced Protein, Gamma-IP10, Interferon-inducible Protein 10, Protein Mob-1, Small-inducible Cytokine B10, Inp10, Mob1, Scyb10)

IP-10, Recombinant, Rat (Cxcl10, C-X-C Motif Chemokine 10, 10kD Interferon gamma-induced
Protein, Gamma-IP10, Interferon-inducible Protein 10, Protein Mob-1, Small-inducible
Cytokine B10, Inp10, Mob1, Scyb10)

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Specifications

IP-10 is a CXC chemokine that signals through the CXCR3 receptor. IP-10 selectively chemoattracts Th1 lymphocytes and monocytes, and inhibits cytokine-stimulated hematopoietic progenitor cell proliferation. Additionally, it is angiostatic and mitogenic for vascular smooth muscle cells. Recombinant rat IP-10 is an 8.6kD protein consisting of 77aa including the four conserved cysteine residues present in CXC chemokines.
Catalog #149691
SourceRecombinant protein corresponding to rat IP-10, expressed in E.coli.
Biological ActivityDetermined by its ability to chemoattract hCXCR3/HEK293 cells using a concentration range of 10-50ng/ml.
Endotoxin<0.1ng/ug (1EU/ug)
AA SequenceIPLARTVRCT CIDFHEQPLR PRAIGKLEII PASLSCPHVE IIATMKKNNE KRCLNPESEA IKSLLKAVSQ RRSKRAP
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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