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You are here:Home » Growth Factors, Cytokines » Growth Factors-GM-CSF » Granulocyte Macrophage Colony Stimulating Factor, Recombinant, Mouse (GM-CSF, Colony-stimulating Factor, CSF, Colony Stimulating Factor 2 (Granulocyte-macrophage), Csf2, Csfgm, MGC151255, MGC151257, MGI-IGM)

Granulocyte Macrophage Colony Stimulating Factor, Recombinant, Mouse (GM-CSF,
Colony-stimulating Factor, CSF, Colony Stimulating Factor 2 (Granulocyte-macrophage),
Csf2, Csfgm, MGC151255, MGC151257, MGI-IGM)

Pricing

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Specifications

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant mouse GM-CSF is a 14.2kD globular protein consisting of 124aa.
Catalog #149706
SourceRecombinant protein corresponding to mouse GM-CSF, expressed in E.coli.
Biological ActivityDetermined by the dose-dependent stimulation of the proliferation of mouse FDC-P1 cells. The ED50 was found to be 0.2ng/ml
Specific Activity5x10e6units/mg
Endotoxin<0.1ng/ug (1EU/ug)
AA SequenceMAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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