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You are here:Home » Molecular Biology » Growth Factors-TNF » Tnfsf14, Recombinant, Mouse (Tumor Necrosis Factor Ligand Superfamily Member 14, CD258, Light, HVEML, HVEM-L)

Tnfsf14, Recombinant, Mouse (Tumor Necrosis Factor Ligand Superfamily Member 14, CD258,
Light, HVEML, HVEM-L)

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Specifications

LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFkB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant mouse LIGHT is a 20.1kD protein containing 183aa.
Catalog #149707
SourceRecombinant protein corresponding to mouse LIGHT, expressed in E.coli.
Endotoxin<0.1ng/ug (1EU/ug)
AA SequenceMRLHQRLGDI VAHLPDGGKG SWEKLIQDQR SHQANPAAHL TGANASLIGI GGPLLWETRL GLAFLRGLTY HDGALVTMEP GYYYVYSKVQ LSGVGCPQGL ANGLPITHGL YKRTSRYPKE LELLVSRRSP CGRANSSRVW WDSSFLGGVV HLEAGEEVVV RVPGNRLVRP RDGTRSYFGA FMV
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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