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You are here:Home » Growth Factors, Cytokines » Growth Factors-Cell Factors » SCF, Recombinant, Rat (Stem Cell Factor, Stem Cell Factor Precursor, c-Kit Ligand, DKFZp686F2250, KIT Ligand, KitL, KITLG, KL-1, Mast Cell Growth Factor, MGF, Steel Factor, SF)

SCF, Recombinant, Rat (Stem Cell Factor, Stem Cell Factor Precursor, c-Kit Ligand,
DKFZp686F2250, KIT Ligand, KitL, KITLG, KL-1, Mast Cell Growth Factor, MGF, Steel Factor,
SF)

Pricing

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Specifications

Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity by signaling through the c-Kit receptor. SCF and c-Kit are essential for the survival, proliferation and differentiation of hematopoietic cells committed to the melanocyte and germ cell lineages. Human SCF manifests low activity on murine cells, while murine and rat SCF are fully active on human cells. Recombinant rat SCF is an 18.4kD polypeptide containing 154aa, which corresponds to the sequence of the secreted soluble form of SCF.
Catalog #149718
SourceRecombinant protein corresponding to rat SCF, expressed in E.coli.
Biological ActivityDetermined by the dose-dependent stimulation of the proliferation of the human TF-1 cell line. The ED50 was found to be <10ng/ml
Specific Activity>1x10e5units/mg
Endotoxin<0.1ng/ug (1EU/ug)
AA SequenceMQEICRNPVT DNVKDITKLV ANLPNDYMIT LNYVAGMDVL PSHCWLRDMV THLSVSLTTL LDKFSNISEG LSNYSIIDKL GKIVDDLVAC MEENAPKNVK ESLKKPETRN FTPEEFFSIF NRSIDAFKDF MVASDTSDCV LSSTLGPEKD SRVSVTKPFM LPPVA
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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