Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Molecular Biology » Growth Factors-NGF » Ngfb, Recombinant, Mouse (Beta-nerve Growth Factor, Beta-NGF, Ngf)

Ngfb, Recombinant, Mouse (Beta-nerve Growth Factor, Beta-NGF, Ngf)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Beta-NGF is a neurotrophic factor structurally related to BDNF, NT-3 and NT-4. These proteins belong to the cysteine-knot family of growth factors that assume stable dimeric structures. Beta-NGF is a potent neurotrophic factor that signals through its receptor Beta-NGFR, and plays a crucial role in the development and preservation of the sensory and sympathetic nervous systems. Beta-NGF also acts as a growth and differentiation factor for B lymphocytes and enhances B-cell survival. The functional form of murine Beta-NGF is a noncovalently disulfide-linked homodimer, of two 13.4kD polypeptide monomers (240aa). The three disulfide bonds are required for biological activity.
Catalog #149733
SourceRecombinant protein corresponding to mouse NGF beta, expressed in E.coli.
Biological ActivityDetermined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The ED50 was found to be <1ng/ml.
Sspecific Activity1x10e6units/mg
Endotoxin<0.1ng/ug (1EU/ug)
AA SequenceMSSTHPVFHM GEFSVCDSVS VWVGDKTTAT DIKGKEVTVL AEVNINNSVF RQYFFETKCR ASNPVESGCR GIDSKHWNSY CTTTHTFVKA LTTDEKQAAW RFIRIDTACV CVLSRKATRR G
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
SourceE. coli
Purity~98% (SDS-PAGE and HPLC)
ConcentrationAs reported
FormSupplied as a lyophilized powder.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links