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You are here:Home » Antibodies » Abs to Chromatin Proteins » Anti -CBX1 (CBX, Chromobox Protein Homolog 1, HP1Hsbeta, Heterochromatin Protein 1 Homolog beta, Heterochromatin Protein p25, M31, Modifier 1 Protein, p25beta)

Anti -CBX1 (CBX, Chromobox Protein Homolog 1, HP1Hsbeta, Heterochromatin Protein 1 Homolog
beta, Heterochromatin Protein p25, M31, Modifier 1 Protein, p25beta)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family . The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq].
Catalog #150223
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 0.3-1ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 2-3ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlA431 Cell Lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to 13aa from near the internal region of CBX1. Species sequence homology: mouse, rat, canine and bovine.
SpecificityRecognizes human CBX1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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