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You are here:Home » Antibodies » Abs to Enzymes » Anti -ABHD14B (NACHT, leucine rich repeat and PYD containing 10, NACHT, LRR and PYD containing protein 10, NACHT, LRR and PYD domains-containing protein 10, NACHT/LRR/pyrin domain-containing protein 10, Nalp10, Napl10, Neuronal apoptosis inhibitor protein 10, N

Anti -ABHD14B (NACHT, leucine rich repeat and PYD containing 10, NACHT, LRR and PYD
containing protein 10, NACHT, LRR and PYD domains-containing protein 10, NACHT/LRR/pyrin
domain-containing protein 10, Nalp10, Napl10, Neuronal apoptosis inhibitor protein 10, N

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Specifications

Clone Host Grade Applications
Polyclonal Goat Purified E B IF
Inhibits autoprocessing of CASP1, CASP1-dependent IL1B secretion, PYCARD aggregation and PYCARD-mediated apoptosis but not apoptosis induced by FAS or BID. Displays anti-inflammatory activity. Plays a role in adaptive immunity through control of dendritic cell-mediated transport of antigen to the lymph nodes from peripheral sites. Required for immunity against C.albicans infection. Involved in the innate immune response by contributing to proinflammatory cytokine release in response to invasive bacterial infection.
Catalog #167340
ApplicationsSuitable for use in Immunofluorescence, ELISA and Western Blot. Other applications not tested.
Recommended DilutionImmunofluorescence: 0.5-1ug/ml
ELISA: 1:128,000
Western Blot: 1-3ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenPeptide with sequence NDLEENSFKTLKFH-C, from the N-terminal domain of the protein sequence (NP_780741.1).
SpecificityRecognizes human ABHD14B (aa188-200). Species sequence homology: Mouse, rat, canine, porcine, bovine
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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