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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -Aminoacyl tRNA Synthase Complex Interacting Multifunctional Protein 1 (AIMP1, SCYE1, Aminoacyl tRNA Synthetase Complex-interacting Multifunctional Protein 1, ARS-interacting Multifunctional Protein 1, EMAP2, EMAPII, Endothelial Monocyte-activating Polypep

Anti -Aminoacyl tRNA Synthase Complex Interacting Multifunctional Protein 1 (AIMP1, SCYE1,
Aminoacyl tRNA Synthetase Complex-interacting Multifunctional Protein 1, ARS-interacting
Multifunctional Protein 1, EMAP2, EMAPII, Endothelial Monocyte-activating Polypep

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Specifications

Clone Host Grade Applications
Polyclonal Goat Purified E B
Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.
Catalog #167344
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:16,000
Western Blot: 0.3-1ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
PurityPurified by ammonium sulfate precipitation.
ImmunogenPeptide with sequence NNDAVLKRLEQK-C, from the N-terminal domain of the protein sequence (NP_004748.2, NP_001135888.1).
SpecificityRecognizes human, mouse, rat AIMP1 / SCYE1. Species sequence homology: Porcine, bovine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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