Induces activation of NF-kappa-B and stimulates production of the proinflammatory chemokine IL-8. Proinflammatory cytokine favoring Th2-type immune responses.
Applications
Suitable for use in Peptide ELISA and Western Blot. Other applications not tested.
Recommended Dilutions
Peptide ELISA: 1:128,000 (detection limit) Western Blot: 0.3-1ug/ml detects ~23kD and ~19kD bands observed in human prostate lysate Optimal dilutions to be determined by the researcher.
Storage and Stability
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Immunogen
Peptide corresponding to RPNRHPESCRASED, from the internal region of human IL-17E (NP_073626.1, NP_758525.1).
Form
Supplied as a liquid in Tris saline, pH 7.3, 0.5% BSA, 0.02% sodium azide.
Purity
Purified by immunoaffinity chromatography.
Specificity
Recognizes human IL-17E. Expected to recognize both isoforms (NP_073626.1, NP_758525.1).
TDS
NCBI
UniProt
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