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You are here:Home » Antibodies » Abs to Growth Factors, Cytokines » Anti -BAFF (B cell Activating Factor , BLyS, CD257, TALL1, THANK, TNFSF13Bm ZTNF4) (APC)

Anti -BAFF (B cell Activating Factor , BLyS, CD257, TALL1, THANK, TNFSF13Bm ZTNF4) (APC)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
BAFF (also known as TALL1, BLyS, and THANK) is a type II transmembrane glycoprotein belonging to the TNF superfamily that has been designated as TNF superfamily member 13B (TNFSF13B). Human BAFF is a 285aa protein consisting of a 218aa extracellular domain, a 21aa transmembrane region and a 46aa cytoplasmic tail.1,2 Human BAFF may be shed from the cell surface by proteolytic cleavage between R133 and Ala134 to yield a soluble form of the protein that is detectable in serum.1,3 BAFF is expressed in peripheral blood mononuclear cells, in spleen and lymph nodes. Its expression in resting monocytes is upregulated by IFN-a, IFN-b, lipopolysaccharide, and IL-10. human and mouse BAFF share 86%aa sequence identity.
Catalog #167631
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 10ul/10e6 cells
Optimal dilutions to be determined by the researcher.
HybridomaMyeloma cells with spleen cells from Balb/c mice.
Absorption 620-650nm
Emission 660-670nm
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. APC is light sensitive.
Clone TypeMonoclonal
IsotypeIgG1
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
PurityPurified by Protein A or G affinity chromatography.
ImmunogenRecombinant corresponding to aa81-285 from human BAFF expressed in E.coli (Q9Y275).
SpecificityRecognizes human BAFF.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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