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You are here:Home » Antibodies » Abs to Cell Surface Proteins » Anti -Ly6K (Lymphocyte Antigen 6 Complex Locus K, CO16, CT97) (APC)

Anti -Ly6K (Lymphocyte Antigen 6 Complex Locus K, CO16, CT97) (APC)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC
Ly6K (Lymphocyte antigen 6 locus K; also known as CO16) is a 26-27kD member of the Ly6 antigen family of molecules. It has restricted expression, being described in testis and skin. Ly6K is found in/on carcinomas, and is known to circulate in normal and tumor patient blood. Mature human Ly6K is a 121aa GPI-linked (presumed) glycoprotein. It is synthesized as a 165aa pre-pro-precursor that contains a 17aa signal sequence, a 121aa mature region (aa18-138), and a 27aa C-terminal pro-peptide. There are two potential splice variants, one that shows a 48aa substitution, and another that shows a 33aa substitution for aa73-165. It is not clear if mouse Ly6K is a true molecular ortholog of human Ly6K. In any event, over aa18-138, human Ly6K shares 39%aa sequence identity with mouse Ly6K.
Catalog #167678
ApplicationsSuitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionFlow Cytometry: 10ul, 10e6 cells
Optimal dilutions to be determined by the researcher.
HybridomaMyeloma cells with spleen cells from Balb/c mice.
Absorption 620-650nm
Emission 660-670nm
Storage and StabilityMay be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. APC is light sensitive.
Clone TypeMonoclonal
IsotypeIgG2a
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in 1ml saline, 0.5% BSA, 0.1% sodium azide. Labeled with Allophycocyanin (APC).
PurityPurified by Protein A or G affinity chromatography.
ImmunogenRecombinant corresponding to aa18-138 from human Ly6K expressed in CHO-S (Q17RY6).
SpecificityRecognizes human Ly6K.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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